Characterization
Poster
Stability of aged ethylene norbornene copolymers used for medical devices
Wowro Sonia Rosine Lago, Univ Paris Sud, Chatenay-Malabry, FranceCaroline Aymes-Chodur, Univ Paris SUD, Chatenay-Malabry, FranceAnge Privat Ahoussou, Université Félix Houphouet Boigny de Cocody, Abidjan, Cote d\'Ivoire Najet Yagoubi, Univ Paris Sud, Chatenay-Malabry, France
This presentation gives an overview of the research on the aging of Ethylene Norbornene Copolymers (ENC) induced by ionizing radiation and photodegradation on order to mimick sterilization and storage aging of medical devices. It is therefore performed on different ENCs with different norbornene rates. These copolymers have interesting physicochemical properties for pharmaceutical and medical applications due to their similar to glass transparency, good chemical resistance and low permeability to gas and water.
The results presented here put in evidence the modifications of the physicochemical properties of the aged ENCs, using experimental techniques such as FTIR (Fourier Transformed Infrared spectroscopy), DSC (Differential Scanning Calorimetry), ATG (Thermogravimetry analysis) and SEC (Steric Exclusion Chromatography).
ENCs stability is influenced by several parameters including the rate of norbornene present in the structure. Nevertheless, the effect of treatment (ionizing radiation or photooxidation) has a real impact on the oxidation induction time of ENCs. The presence of oxidations compounds that can act as oxidation protectoris is also highlighted in this study. In a next step, it would be interesting to identify them and determine their specific toxicity.